Anti-Inflammatory Drugs Nonsteroidal (Nsaids): Everything You Need to Know

The use of chemical substances to improve the pain and inflammation is one of the needs of humanity. Learn the benefits and risks of anti-inflammatory drugs.

Non-Steroidal Antiinflammatory Drugs

The anti-inflammatory drugs (Nsaids) are frequently dismissed, either for medical indication or by pharmaceutical advice. In both situations, there is that underline the need to ensure the takes safe of these medicines, in particular in patients with risk factors for complications gastrointestinal or cardiovascular.

The marketing of these drugs in certain doses is sold over the counter, without the need for prescription, which increases the responsibility of those who take the medication.

This therapy group is especially effective in the treatment of inflammation the level of the osteoarticular. All nsaids have three basic effects:

  • Antipyretic (against fever);
  • Analgesic (reduces pain);
  • Anti-inflammatory.

 

WHAT ARE THE ANTI-INFLAMMATORY NOT STEROIDS?

The Nsaids are recommended in situations of inflammation and pain associated. Are advised for the relief of pain in chronic diseases, such as arthrosis, rheumatoid arthritis and low back pain, and in acute situations, such as minor surgery, interventions dental, menstrual pain, generalized pain, migraines, and gout.

WHAT ARE THE SIDE EFFECTS OF NSAIDS?

The anti-inflammatory non steroids (Nsaids) are compounds that block the formation of prostaglandins, which are substances produced normally by the body and involved in various physiological functions, such as, for example, the protection of the stomach lining, regulating blood pressure, the pain and the inflammation.

So, when they block the synthesis of prostaglandins, nonsteroidal anti-inflammatory drugs relieve pain and inflammation, interfere with the protective functions of these substances. It is for this reason that, among its side effects are stomach upset and gastrointestinal bleeding.

The risk of problems increases with long-term use of Nsaids. Should be used with caution in patients who have gastric ulcers and at that are anti-coagulated with antagonists of vitamin K. in children and adolescents should not be medicated with acetylsalicylic acid.

WHAT ARE THE RISKS OF ANTI-INFLAMMATORY DRUGS?

These medicines have been the target of several security reviews, not only the cardiovascular but also the gastrointestinal and cutaneous.

Patients with symptoms indicative of disturbances in gastrointestinal or with a history suggestive of gastric ulceration or intestinal, arterial hypertension not controlled, congestive heart failure, ischaemic heart disease established peripheral arterial disease, and/or cerebrovascular disease, should be given particular attention at the time of the waiver AINE’s.

However, the risk-benefit ratio remains positive, although this does not exclude the possibility of an increase in the occurrence of thromboembolic events, such as heart attacks or strokes, especially when used in high doses and in long-term treatment.

The risks associated with these therapies can be minimized by using the lowest effective dose for the shortest time necessary to control symptoms.

WHO SHOULD NOT TAKE ANTI-INFLAMMATORY DRUGS?

Should ask your doctor before taking an Nsaid if you:

  • Already suffered adverse effects when taking other medicines in the same therapeutic class;
  • Has a greater risk of bleeding in the stomach;
  • Has stomach problems, including heartburn;
  • You have high blood pressure, heart disease, liver cirrhosis or kidney disease;
  • Suffers from asthma;
  • Take a diuretic medicine.

IN CONCLUSION

Although the anti-inflammatory drugs are one of the groups of medications most frequently consumed throughout the world and, by consequence, of the most studied, there are risks associated with taking them.

Thus, the intake should always be accompanied by counselling by a health professional that explain the daily dosages, the time of treatment and the risks that may be associated.

Therefore, as a general rule, the treatment with anti-inflammatory non steroids should be done under professional advice and for the shortest possible time to symptomatic relief.